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Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 to the Lively metabolite N-desmethyldiazepam, and is particularly hydroxylated by CYP3A4 to the Lively metabolite temazepam.Usually do not drive or work hefty machinery right up until you know the way taking diazepam tablets with opioids influences you.So, for individuals who're asking: “Ca